Opera Music Improves Heart Transplant Survival

Sara Maines of The MaineStudio

Not kidding... This research was actually published in the Journal of Cardiothoracic Surgery in 2012. I should add that the research was done in mice rather than humans and won the 2013 Ig Prize in Medicine.

To quote from the abstract:

"recipients of a B6 cardiac graft that were exposed to opera music and Mozart had significantly prolonged allograft [transplant] survival... whereas those exposed to a single sound frequency (100, 500, 1000, 5000, 10,000, or 20,000 Hz) or Enya did not... Our findings indicate that exposure to opera music, such as La traviata, could affect such aspects of the peripheral immune response as generation of regulatory CD4+CD25+ cells and up-regulation of anti-inflammatory cytokines, resulting in prolonged allograft [transplant] survival. "

Wonder if this research can apply to other surgical healing and survival...

Reference:
Auditory stimulation of opera music induced prolongation of murine cardiac allograft survival and maintained generation of regulatory CD4+CD25+ cells. Journal of Cardiothoracic Surgery 2012, 7:26 doi:10.1186/1749-8090-7-26

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Fecal Transplantation Administered Through the NOSE!

Fecal transplant is nothing new as it has been around since the 1950's... It is used to treat multi-drug resistant clostridium dificile infection by replacing the "bad" gut bacteria with normal "good" bacteria. However, what is new is the fact that such fecal transplantation is being administered through the nose using a tube threaded into the small bowel. [Thanks to @GuildfordENT who brought this to my attention!]

Historically, such fecal transplantation (aka fecal bacteriotherapy) was performed via multiple infusions via enema (uncomfortable for both the physician as well as the patient) or via colonoscope. Although first described being done in humans in 1958, it was never really seriously studied until the mid-1980's. Even before humans, it had been performed in animals by veterinarians for centuries.

In any case, there has been new literature supporting the use of nasoduodenal tubes to administer poop via the nose. With nasoduodenal tubes, a tube is threaded through the nose, past the stomach, and into the small bowel.

Now keep in mind that the stool actually NEVER comes into contact with the nose. It is contained within an impermeable tube at all times, so it is not quite as gross as you might think (though mentally, there may still be an emotional ick factor present).

Another approach being considered is encapsulating the poop inside enteric-coated capsules so a patient can theoretically swallow the pill-containing poop.

Media Mention:
Doctors save patient from deadly superbug by transplanting faeces through his NOSE. MailOnline

Reference:
Duodenal infusion of donor feces for recurrent Clostridium difficile. New England Journal of Medicine. 2013 Jan 31;368(5):407-15. doi: 10.1056/NEJMoa1205037. Epub 2013 Jan 16.

Same poop, different gut. The Scientist 11/3/105/2/13

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Realistic Face Masks

With halloween coming up and more face transplants occurring to address severe facial disfigurement, it was only a matter of time when a commercial company can recreate a 3-dimensional replica of a person's face. Unlike medical facial transplants which creates a face that's a cross between the donor face and the patient's face prior to disfigurement, these faces are perfect replicas down to scars, blood vessels, skin pores, etc.

Well, there's a Japanese company called Real-f 3 Dimension Photo Forms that can produce a realistic mask of yours or anybody else's face.

But... they are expensive running $4000 - $6000.

Check out more realistic face masks the company has created on their facebook page.

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