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Showing posts with label dificile. Show all posts
Showing posts with label dificile. Show all posts

Thursday, 2 May 2013

Fecal Transplantation Administered Through the NOSE!

Posted on 14:16 by Unknown
Fecal transplant is nothing new as it has been around since the 1950's... It is used to treat multi-drug resistant clostridium dificile infection by replacing the "bad" gut bacteria with normal "good" bacteria. However, what is new is the fact that such fecal transplantation is being administered through the nose using a tube threaded into the small bowel. [Thanks to @GuildfordENT who brought this to my attention!]

Historically, such fecal transplantation (aka fecal bacteriotherapy) was performed via multiple infusions via enema (uncomfortable for both the physician as well as the patient) or via colonoscope. Although first described being done in humans in 1958, it was never really seriously studied until the mid-1980's. Even before humans, it had been performed in animals by veterinarians for centuries.

In any case, there has been new literature supporting the use of nasoduodenal tubes to administer poop via the nose. With nasoduodenal tubes, a tube is threaded through the nose, past the stomach, and into the small bowel.

Now keep in mind that the stool actually NEVER comes into contact with the nose. It is contained within an impermeable tube at all times, so it is not quite as gross as you might think (though mentally, there may still be an emotional ick factor present).

Another approach being considered is encapsulating the poop inside enteric-coated capsules so a patient can theoretically swallow the pill-containing poop.

Media Mention:
Doctors save patient from deadly superbug by transplanting faeces through his NOSE. MailOnline

Reference:
Duodenal infusion of donor feces for recurrent Clostridium difficile. New England Journal of Medicine. 2013 Jan 31;368(5):407-15. doi: 10.1056/NEJMoa1205037. Epub 2013 Jan 16.

Same poop, different gut. The Scientist 11/3/105/2/13
Read More
Posted in bacteria, bug, c dif, dificile, enema, fecal, infection, nose, poop, super, transplant, transplantation, treatment | No comments
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  • lip
  • lip reading
  • liquid
  • lisa
  • lisinopril
  • list
  • listen
  • listerine
  • lithium
  • live
  • liver
  • living
  • lizard
  • local
  • location
  • lock
  • locked
  • long
  • loss
  • lost
  • loud
  • loudness
  • loudon
  • louisiana
  • low
  • lpr
  • lsn
  • lump
  • lung
  • lymphoma
  • lytro
  • mac
  • machine
  • macrophage
  • made
  • magazine
  • maggot
  • maggots
  • magic ears
  • magnetic
  • mail
  • major
  • make
  • mal
  • male
  • malpractice
  • mammogram
  • man
  • management
  • manassas
  • mandatory
  • mandible
  • mandibular
  • many
  • map
  • marcaine
  • mariana
  • marie
  • marilyn
  • marinomed
  • marketing
  • maroney
  • marriage
  • mask
  • mass
  • massage
  • master
  • maxillary
  • maxwell
  • mayo
  • mca
  • mckayla
  • mcmath
  • md
  • measles
  • measure
  • meat
  • med
  • medal
  • medgadget
  • media
  • medial
  • medical
  • medical mystery
  • medicare
  • medication
  • medicine
  • medigus
  • medtronic
  • mega
  • melatonin
  • melena
  • membrane
  • men
  • meniere's
  • meningioma
  • meningitis
  • mensa
  • merck
  • merger
  • mesh
  • messaging
  • meta
  • metabolism
  • metabolizer
  • metal
  • metallic
  • meth
  • methamphetamine
  • methylamphetamine
  • methylene
  • mexico
  • mi
  • mic
  • micah johnson
  • mice
  • michael
  • microbial
  • microbiota
  • microflora
  • microphone
  • microscope
  • microscopic
  • microwave
  • middle
  • migraine
  • milk
  • minaj
  • mineral
  • mineral oil
  • minimally
  • minimally invasive
  • miradry
  • mirror
  • misdiagnosis
  • miserable
  • miss america
  • miss korea
  • miss oregon
  • miss usa
  • miss wisconsin
  • missed
  • mit
  • mms
  • mobile
  • mod
  • model
  • modern
  • modification
  • mohler
  • mom
  • money
  • monitoring
  • monroe
  • more
  • morning
  • morphine
  • mortality
  • most
  • mother
  • mother's
  • motley crue
  • mouth
  • mouthwash
  • mouthwatering
  • movement
  • movie
  • mozart
  • mri
  • mrsa
  • msnbc
  • mucosa
  • mucosal
  • mucus
  • mumps
  • mundane
  • murmur
  • muscle
  • music
  • musicians
  • my fair lady
  • myoclonus
  • myoguide
  • myringotomy
  • mystery
  • myth
  • nadal
  • nail
  • name
  • nar
  • narcotic
  • nares
  • narrow
  • nasacort
  • nasal
  • nasal congestion
  • nasal obstruction
  • nasal packing
  • nasal spray
  • nasopure
  • nate bell
  • nathan sykes
  • nation
  • national institute of health
  • natural
  • NBC
  • ncs
  • necessity
  • neck
  • needle
  • negative
  • neglect
  • negligent
  • neilmed
  • nejm
  • nerve
  • netatmo
  • neti-pot
  • netter
  • network
  • neural
  • neuralgia
  • neuro
  • neuroanatomy
  • neurologica
  • neurology
  • neuroma
  • neuropathy
  • Neuropsychiatric
  • neurosurgeon
  • New
  • new england
  • new jersey
  • new york times
  • newborn
  • news
  • newsletter
  • newspaper
  • nexium
  • next
  • nfl
  • nicki
  • night
  • nightclub
  • nih
  • nina
  • nissen
  • nitrate
  • nmda
  • no
  • nobel
  • nodule
  • nodules
  • noise
  • noisy
  • non
  • non-acid
  • non-acidic
  • non-organic
  • non-par
  • non-sedated
  • non-verbal
  • normal
  • northern
  • northern virginia
  • nose
  • nosebleed
  • nosejob
  • nostril
  • nostrils
  • not
  • note
  • nova
  • nrr
  • nsaid
  • nsaids
  • nuclear
  • number
  • nurse
  • nutrition
  • nutritional
  • ny
  • NYT
  • oae
  • observation
  • obstetrics
  • obstruction
  • obstructive
  • obstructive sleep
  • ocd
  • ocean
  • ochsner
  • off
  • office
  • oil pulling
  • oklahoma
  • old
  • older
  • olfactory
  • olympic
  • omeprazole
  • one
  • online
  • open
  • opera
  • operating
  • operating room
  • operation
  • operative
  • operavox
  • ophthalmic
  • opinion
  • opioid
  • opposite
  • optimization
  • options
  • or
  • oral
  • oral mass
  • oral sex
  • oralair
  • orbit
  • orbital
  • orchestra
  • organic
  • ortho
  • orthopedic
  • orthopedics
  • osa
  • osha
  • otalgia
  • otc
  • oticon
  • otitis
  • otoacoustic
  • otolaryngology
  • otoscope
  • otovent
  • out
  • outbreaks
  • outer
  • output
  • outrageous
  • over
  • overdose
  • overlay
  • owl
  • oxidant
  • oxygen
  • pa
  • pacifier
  • packing
  • page
  • pain
  • painting
  • palsy
  • paltrow
  • pandas
  • paper
  • paper patch
  • papillary
  • papilloma
  • papillomas
  • papillomatosis
  • paradoxical
  • paradoxical vocal cord
  • paralysis
  • paralyzed
  • paralyzed vocal cord
  • parasitic
  • parent
  • parkinson's disease
  • parotid
  • parotidectomy
  • partial
  • past
  • patch
  • path
  • pathology
  • pathway
  • patient
  • patient portal
  • patient satisfaction
  • patient satisfaction score
  • pay
  • pediatric
  • pen
  • pencil
  • penis
  • pennsylvania
  • pepcid
  • pepsin
  • peptest
  • perfection
  • perforation
  • perform
  • performance
  • perfortion
  • periodic
  • peripheral
  • permanent
  • peroxide
  • person
  • personal
  • personality
  • peru
  • pettygrove full
  • PFAPA
  • ph
  • pharmacy
  • pharyngitis
  • pharynx
  • phillips
  • phlegm
  • phlegmy
  • phonak
  • phone
  • photo
  • photograph
  • photoshop
  • Physician
  • physics
  • picker
  • picture
  • pida
  • piercing
  • pill
  • pillow
  • pinterest
  • pipes
  • pitch
  • pitch perfect
  • pitcher
  • placebo
  • plants
  • plastic
  • plate
  • pluck
  • plug
  • plugs
  • PND
  • pneumonia
  • pocket
  • point
  • poison
  • poisoning
  • poke
  • policy
  • polio
  • politician
  • pollen
  • polyp
  • pool
  • poop
  • poor
  • pop
  • popping
  • popular
  • popularity
  • pork
  • port
  • portable
  • pose
  • position
  • positive
  • possible
  • post
  • post-nasal drainage
  • posterior
  • posterior tongue tie
  • postop
  • pouch
  • pound
  • pov
  • powder
  • power
  • ppi
  • practice
  • preamp
  • prednisone
  • pregnancy
  • pregnant
  • premium
  • prescription
  • present
  • presentation
  • presentations
  • preservative
  • president
  • presley
  • press ganey
  • pressure
  • prevacid
  • prevent
  • price
  • prick
  • prilosec
  • prince william
  • Prince William Hospital
  • principle
  • private
  • prize
  • pro
  • probe
  • problem
  • problems
  • procedure
  • process
  • product
  • profanity
  • professional
  • professor
  • prognosis
  • program
  • programming
  • progress
  • projection
  • pronunciation
  • proof
  • protect
  • protection
  • protocol
  • proton
  • provider
  • pseudo
  • pseudoephedrine
  • pterygopalatine
  • public
  • publication
  • publish
  • pulling
  • pulse
  • pump
  • purchase
  • purify
  • pus
  • putney
  • pyridostigmine
  • q
  • q-tips
  • q&a
  • qb
  • qliqconnect
  • qnasl
  • quack
  • quality
  • quarterback
  • question
  • radiation
  • radical
  • radiologist
  • radiology
  • rafael
  • raft
  • ragweed
  • range
  • ranitidine
  • ranking
  • rapid
  • rapid rhino
  • rash
  • raspy
  • RAST
  • rate
  • rating
  • rationing
  • ravens
  • rca
  • reaction
  • reader
  • realistic
  • reason
  • rebound
  • receptor
  • recipe
  • reconstruction
  • record
  • recording
  • records
  • recovery
  • rectal
  • rectum
  • recurrence
  • recurrent
  • red
  • red bull
  • reddit
  • reduce
  • reduction
  • reena
  • reese
  • reflux
  • region
  • regular
  • regurgitated
  • related
  • release
  • relief
  • religion
  • removal
  • Remove Tonsil Stones
  • removing
  • repair
  • replacement
  • report
  • research
  • researchers
  • resection
  • respiratory
  • respiratory flutter
  • response
  • rest
  • restaurant
  • reston
  • restricted
  • results
  • retainer
  • revenue
  • reverberation
  • reversal
  • review
  • rhinitis
  • rhinoplasty
  • rhys morgan
  • ride
  • ringing
  • rinse
  • risk
  • risk of death
  • risks
  • river
  • rivera
  • roar
  • roaring
  • robot
  • robotic
  • rocker
  • roof
  • room
  • rrp
  • rsa
  • rss
  • rubella
  • ruling
  • runny
  • runny nose
  • rush
  • rx
  • safe
  • safe and sound
  • safety
  • salah
  • saline
  • saliva
  • salivary
  • salman
  • salon
  • salt
  • same
  • sammy
  • sampter
  • sanitation
  • santa claus
  • satisfaction
  • save
  • savory
  • scabbing
  • scale
  • scam
  • scan
  • scandal
  • scanner
  • scans
  • scar
  • scare
  • scarf
  • scd
  • schedule
  • schwannoma
  • science
  • science friday
  • scientist
  • SCIT
  • scope
  • scopolamine
  • score
  • scraping
  • scream
  • screaming
  • screening
  • screw
  • screwdriver
  • scrubbed out
  • SD
  • seahawks
  • search
  • seattle
  • seaweed
  • secure
  • security
  • sedated
  • sedation
  • seismology
  • self
  • selsap
  • sensation
  • sense
  • sensitive
  • sensitivity
  • sensorineural
  • sensory
  • seo
  • separated
  • sepsis
  • septal
  • septo
  • septoplasty
  • septum
  • serum
  • service
  • severe
  • sex
  • sexy
  • sgr
  • shape
  • shapiro
  • share
  • sharp
  • shawn feeney
  • shenandoah
  • sheryl crow
  • shift
  • shimmer
  • shooting
  • short
  • shortness
  • shot
  • shots
  • shoulder
  • show
  • shower
  • si
  • sick
  • side
  • side effect
  • side effects
  • sided
  • sids
  • siemens
  • signature
  • sill
  • silver
  • silver nitrate
  • sing
  • singer
  • singer's
  • singing
  • singulair
  • singultus
  • sinonasal
  • sinuplasty
  • sinus
  • sinus headache
  • sinus surgery
  • sinusitis
  • sister
  • site
  • size
  • skin
  • skin patch
  • skull
  • slate
  • sleep
  • sleep apnea
  • SLIT
  • slow
  • SLP
  • sluder's
  • smart
  • smarter
  • smartphone
  • smash
  • smell
  • smith
  • smoking
  • smooth
  • sms
  • snake
  • snap
  • sneeze
  • SNHL
  • snore
  • snoring
  • snot
  • so
  • social
  • social media
  • socialism
  • soda
  • sodium
  • sofia
  • soft
  • sohier
  • solution
  • somatoparaphrenia
  • sophono
  • sorbet
  • sore
  • sore throat
  • sound
  • soundbite
  • soundfit
  • sounds
  • sour
  • sparing
  • spasm
  • spasmodic
  • spat
  • specialist
  • specimen
  • spect
  • speech
  • speech therapy
  • sperm
  • sphenopalatine
  • spider
  • spinal
  • spine
  • spinning
  • spit
  • splitting
  • sponsored
  • sport
  • sports
  • spouse
  • spray
  • sprays
  • spread
  • spring
  • sputum
  • squid
  • stabbing
  • staff
  • stage
  • stallergenes
  • stapedial
  • stapedius
  • staph
  • staple
  • star
  • state
  • statin
  • statistic
  • statistics
  • steelers
  • stem
  • stenosis
  • steroid
  • steve jobs
  • stick
  • sticky
  • stimulation
  • sting
  • stoma
  • stomach
  • stomach wrap
  • stone
  • stones
  • stool
  • story
  • straighten
  • strained
  • strap
  • strength
  • strep
  • Streptococcus
  • stress
  • strict
  • stridor
  • strobe
  • stroboscopy
  • stroke
  • structure
  • stuck
  • study
  • stupid
  • stutter
  • subject
  • sublingual
  • submandibular
  • submaxillary
  • submental
  • submucus
  • subscriber
  • subscription
  • success
  • such
  • suction
  • sudafed
  • sudden
  • sue
  • suffer
  • summary
  • sun
  • sunburn
  • sunlight
  • super
  • superior
  • supplement
  • supplements
  • supreme
  • surface
  • surgeon
  • surgery
  • surgical
  • survey
  • survival
  • suzi quatro
  • swab
  • swallow
  • swearing
  • sweating
  • sweden
  • sweet
  • swelling
  • swimmer
  • swimming
  • swollen
  • symptom
  • symptoms
  • syndrome
  • synthetic
  • system
  • systemic
  • T&A
  • table
  • tablet
  • tackle
  • talk
  • talking
  • talks
  • tape
  • target
  • targeted
  • taste
  • tattoo
  • taylor
  • tea
  • tear
  • technique
  • technology
  • tectorial
  • ted
  • teddy
  • tedmed
  • teen
  • teeth
  • telephone
  • television
  • temperature
  • template
  • temporalis
  • temporary
  • tennis
  • tensor tympani
  • teratoma
  • terminal
  • tesla
  • test
  • tested
  • testicle
  • testing
  • tests
  • texas
  • textbook
  • the band
  • the counter
  • the doctors
  • theory
  • therapy
  • thigh
  • thinking
  • third
  • thomas
  • thought
  • threatening
  • threshold
  • throat
  • throat cancer
  • Throat Stones
  • through
  • throw
  • thyroid
  • thyroidectomy
  • tia
  • tic
  • tickle
  • tie
  • tiger
  • tight
  • tighten
  • time
  • time machine
  • time-out
  • times-democrat
  • timing
  • tinnitus
  • tip
  • tissue
  • titanium
  • tms
  • tne
  • to
  • toddler
  • tolerance
  • tongue
  • tongue patch
  • tongue tie
  • tonsil
  • tonsil stones
  • tonsillectomy
  • tonsillitis
  • tonsilloliths
  • tonsilolith
  • toothbrush
  • toothpaste
  • top
  • top doctor
  • torax
  • total
  • tower
  • toy
  • toys
  • trach
  • tracheostomy
  • traffic
  • trailer
  • trans
  • transcranial
  • translator
  • transmit
  • transparency
  • transplant
  • transplantation
  • trap
  • trauma
  • travel
  • treat
  • treatment
  • tree
  • tremor
  • triad
  • trial
  • triangle
  • tricalm
  • trigger
  • trimester
  • trimmer
  • trip
  • tripod
  • trivia
  • trouble
  • troy
  • true
  • tts
  • tube
  • tubes
  • tuboplasty
  • tumor
  • tunnel
  • turbinate
  • TV
  • tweaker
  • tween
  • tweet
  • tweezer
  • twitter
  • tylenol
  • tympanic
  • tympanoplasty
  • type
  • types
  • ufc
  • ulcer
  • ulerative
  • ultrasound
  • ultraviolet
  • umami
  • unable
  • unapproved
  • under
  • underlay
  • understand
  • understudy
  • united states
  • universal
  • universal precautions
  • unnecessary
  • unpublished
  • unsafe
  • unsedated
  • upper
  • upper lip tie
  • upper respiratory infection
  • uppp
  • URI
  • urine
  • us
  • usage
  • use today
  • uv
  • uvula
  • va
  • vac
  • vaccine
  • vacuum
  • valsalva
  • valve
  • vampire
  • vancouver
  • vcd
  • vegf
  • vein
  • velopharyngeal
  • venous
  • vent
  • ventilation
  • vergara
  • verisante
  • verisign
  • version
  • vertebra
  • vertigo
  • vessel
  • vestibular
  • vial
  • vibration
  • vibrato
  • vice president
  • video
  • viewed
  • villain
  • viral
  • viral cold
  • virginia
  • virus
  • vision
  • vital signs
  • vitamin
  • vitamins
  • vivian
  • vivitouch
  • vocal
  • vocal cord
  • vocal cord dysfunction
  • vocal cord paralysis
  • vocal cords
  • vocal range
  • voice
  • voice council
  • voicebox
  • volume
  • vomit
  • vpi
  • wait
  • wall street journal
  • wanted
  • warning
  • warrenton
  • washington
  • washington post
  • washingtonian
  • wasp
  • water
  • watering
  • wax
  • waxvac
  • way
  • weak
  • weakness
  • wealth
  • wearing
  • web
  • webpage
  • Website
  • week
  • weekday
  • weekend
  • weeks
  • weight loss
  • weird
  • wendy nguyen
  • what
  • what to do
  • wheezing
  • when
  • where
  • whisper
  • whistle
  • whistling
  • white
  • white balance
  • who
  • whole
  • whoop
  • whooping
  • whooping cough
  • why
  • wickr
  • widex
  • wife
  • wilson
  • winchester
  • window
  • wine
  • wipe
  • wire
  • wireless
  • wiring
  • wisconsin
  • wisestamp
  • withdrawal
  • witherspoon
  • without
  • without incision
  • woman
  • womb
  • women
  • words
  • work
  • worker
  • working
  • works
  • workup
  • world
  • worse
  • worst
  • worth
  • wp
  • wrong
  • wrongful
  • wsj
  • x-ray
  • xlear
  • xylitol
  • yankees
  • years
  • yellow
  • yodel
  • yoga
  • young
  • youth
  • youtube
  • z-pack
  • zac efron
  • zantac
  • zenker's
  • zeta
  • zygomatic

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